Senior Director, End-to-End Digital Strategy & Innovation Dublin or Cork

Are you ready to set the guiding vision that connects planning to patient and turns ambition into measurable outcomes? Reporting to the Vice President of Technical Operations, you will lead the end-to-end digital strategy that powers how we manufacture, assure quality, plan supply, and connect with customers—accelerating reliable delivery of new modalities to people who need them most. This is a high-impact, enterprise role at the intersection of strategy, technology, and operations. You will shape the Industry 4.0 vision, build an integrated investment roadmap, and orchestrate execution across manufacturing, quality, supply chain, and IT/OT. Your work will enable real-time visibility and decisioning, predictive planning, customer connectivity, and above-site capabilities—creating a durable competitive advantage and a step-change in patient and customer experience. How will you turn a bold vision into scalable digital capabilities that endure? Accountabilities: Digital North Star: Define a hard-working, end-to-end digital strategy aligned to business goals, with a clear value case and narrative that inspires broad followership. Portfolio and Roadmap: Build and maintain an integrated, sequenced portfolio of digital investments that creates competitive advantage, balancing speed, risk, capacity, and value realization. Metrics that Matter: Establish success factors and critical metrics; maintain a transparent scorecard and outcomes narrative; report quarterly progress to senior leadership and governance forums. Cross-Functional Orchestration: Serve as strategic lead for Connected Factory and Supply Chain initiatives; align Manufacturing, Quality, Sites, and IT/OT on end-to-end connectivity and value. Operating Model Design: Define and evolve the operating model, funding approach, and resource strategy (including MTP/LTP planning) to scale digital and data capabilities across Technical Operations. Change Leadership: Sponsor change networks, training strategies, communications, and benefits realization to drive adoption and sustain new ways of working. Innovation Ecosystem: Build strong partnerships across sites, enterprise teams, technology vendors, and industry groups to bring outside-in insights and accelerate innovation. Data, IT/OT and Advanced Analytics: Identify and close gaps in data, systems, and infrastructure; influence investments for autonomous manufacturing, connected factory, and supply chain analytics and advanced technical analytics. Story Amplification: Communicate achievements, lessons, and ambitions across the network to build momentum and reinforce a culture of innovation and continuous improvement. External Representation: Represent the organization on enterprise programs and relevant national councils; collaborate with industry bodies (e.g., BioPhorum, ISPE) to benchmark and adopt standard methodologies. Funding and Partnerships: Partner with government agencies and other bodies to secure digital grants and ensure compliant, timely milestone delivery. Operations Data Strategy and Governance: Ensure consistent data governance, integrity, and accessibility across the enterprise; maintain the roadmap of data products to support AI ambitions. Essential Skills/Experience:

• Experience: Minimum 15 years of progressive experience, with a consistent track record leading broad digital transformation, preferably across end-to-end supply chain in biopharma or highly regulated manufacturing - E2E Technical Operations Expertise: Deep understanding of Supply Chain, planning, manufacturing, quality/QC, logistics, and customer connectivity, and how digital enables end-to-end value - Strategic Leadership: Demonstrated ability to set vision and strategy, translate into actionable portfolios and roadmaps, and deliver measurable outcomes at enterprise scale - Influence and Storytelling: Exceptional communication and executive presence; able to simplify complexity into compelling narratives that secure consensus across senior leadership and cross-functional teams - Innovation Perspective: Entrepreneurial, outside-in orientation with strong awareness of industry trends and the ability to challenge the status quo and unlock new value pools - Transformation Delivery: Hands-on leadership of change management, adoption, and benefits realization; high bias for action and resilient in navigating organizational complexity - Operational Excellence & Data: Working knowledge of operational excellence, data ecosystems and governance, and the intersection of IT/OT in manufacturing and quality environments Desirable Skills/Experience:
• Industry Engagement: Experience with BioPhorum, ISPE, or similar forums; participation in national or internal digital councils - Advanced Manufacturing & Analytics: Familiarity with autonomous manufacturing, connected factory, IT/OT convergence, and advanced analytics/AI in operations - Funding & Partnerships: Experience engaging with agencies such as IDA and handling external grants or co-funded initiatives When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Our mission brings diverse authorities side by side to tackle hard problems that matter for people with rare and devastating diseases, pairing the energy of biotech with the scale, resources, and rigor of a global organization. You will shape the digital backbone of our value chain using innovative Industry 4.0, advanced analytics, and IT/OT convergence, while growing in a culture that values kindness alongside ambition and gives you the autonomy to stretch beyond your lane. Here, your ideas can move from concept to enterprise capability—and your impact will be felt in the speed, reliability, and quality of medicines reaching patients who have the most to gain. Call to Action: If you are ready to define the North Star and lead an end-to-end digital transformation with tangible outcomes for patients and the business, step forward and shape what comes next!

Date Posted

29-May-2026

Closing Date

25-Jun-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.