Associate Director - Tissue Diagnostics

Job Title: Associate Director, Tissue Diagnostics

Location:  Cambridge

Salary: competitive

Introduction to role:

Precision Medicine & Biosamples within AstraZeneca focuses on matching medicines to those patients who will benefit from them most and delivers companion or complementary diagnostic assays that align with the drug development process and enable personalised healthcare approaches within our clinical portfolio.

Accountabilities:

We are looking for an Associate Director of Tissue Diagnostics to develop industry-leading diagnostic tests enabling AstraZeneca’s Oncology drug development. The successful candidate will leverage internal R&D and CAP/CLIA lab capabilities to develop highly innovative diagnostic platforms based on multiplex immunohistochemistry and proteomics. This requires wide collaboration with our internal lab-based teams, cross-functionally within AstraZeneca as well as with external academic or industry collaborators. You will be a credible scientific and technical leader, driving future innovation and helping AZ reach our 2030 bold ambition to eliminate cancer as a cause of death.

As a senior member of the Precision Medicine and Biosamples team, you will ensure that all activities are delivered demonstrating behaviours and values aligned to the AstraZeneca code of conduct and supporting policies, standards, and procedures - including compliant management of budget, safety, health, and environment.

Essential Skills/Experience:

• Masters/PhD or equivalent experience in a relevant area

• Hands-on experience developing tissue-based diagnostic assays (e.g. immunohistochemistry, in situ hybridization) in a regulated environment (e.g. under In Vitro Diagnostics development standards or within a CAP/CLIA laboratory)

• Evidence of driving laboratory-based innovation

• Ability to lead complex scientific projects and collaborate across teams in a matrix environment and with external partners

• Ability to communicate clearly and influence stakeholders while keeping balanced and objective views

Desirable Skills/Experience:

• Expertise with one, or more, multiplex protein technologies (for example, but not limited to, multiplex immunohistochemistry, immunofluorescence, spatial omics, proteomics)

• Experience with digital pathology and digital image analysis

• Understanding of drug clinical trial and companion diagnostics co-development

• Understanding of diagnostic development and clinical testing standards and regulations such as Good Clinical Practice, CAP/CLIA, relevant FDA and EMA guidelines.

• Experience interacting with In Vitro Diagnostics regulatory authorities.

• Experience as a team leader or line manager

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca?

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us. With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing cutting-edge science with the latest technology to achieve breakthroughs. Backed by investment, we are aiming to deliver 6 new molecular entities by 2025. A place built on courage, curiosity and collaboration. We make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Pioneers of collaborative research we have built an unrivalled scientific community both internally and externally. Fusing academia and industry, we have united some of the world's foremost medical centres. Working seamlessly and inclusively, together we expedite research in some of the hardest-to-treat cancers. Have the opportunity to build a rewarding and meaningful career as part of the team committed to improving the lives of millions with cancer.

Are you ready to make a difference? Apply today and join us in our mission to improve global public health!

So, what’s next?

Complete your application before the below closing date.

We welcome your application no later than 31st January 2025

Where can I find out more?

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