Research Associate Scientist, Bioscience In vivo

As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026.  Find out more information here:    

Kendall Square Press Release

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, significant medicines and healthcare solutions that enrich the lives of patients. The vision of AstraZeneca Early Respiratory & Immunology (Early R&I) is centered on delivering life-changing products that advance world health and help fight and cure disease. Early R&I is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. We are building new capabilities to support our growth in immunology and autoimmune diseases, and we have an exciting opportunity for an in vivo scientist looking to help bring new medicines to patients.

As a part of a growing in vivo Bioscience team within the Early R&I department, we are seeking a highly motivated research associate with diverse laboratory skills to join our collaborative team. This candidate would ideally have experience in immunology or related subject area. This is a lab-based position. The role will initially be based in Waltham, MA within AstraZeneca’s state-of-the-art laboratories where you will follow the science to help drive innovation and advance medicine to help improve patient lives. In 2026 we will be located at the new innovative facilities in Kendall Square Cambridge.

Main Duties and Responsibilities

In this role, you will be an experimental scientist within Early Respiratory and Immunology Department focusing on developing therapeutics for the treatment of immune and autoimmune diseases such as SLE, colitis and arthritis using mouse models. You will generate preclinical and translational data in support of key portfolio programs and drive technical excellence in bioscience research. Expertise in flow cytometry, multiplex cytokine read-outs, qPCR is critical. The role will sometimes involve implementing protocols over timelines that extend outside of normal working patterns.

• Excellent hands-on in vivo skills including administering candidate drugs and collecting a range biological samples in mice.

• Responsible for maintaining the highest standards of animal welfare and ethical compliance as well as data integrity.

• Contribute to the evaluation and interpretation of primary data as well as writing reports and summaries.

• Supporting drug discovery projects to meet their objectives by acting as an effective and creative team member.

• You will benefit from daily interaction and collaboration with highly accomplished scientists and the position offers a unique opportunity to work in a dynamic and innovative environment developing your career at the interface of research and drug discovery.

• Encouragement and support will be provided to help the individual develop specialist knowledge and skill sets.

Requirements

• Relevant degree in biology, immunology or relevant discipline is required with a bachelor or master’s degree and 2+ years of relevant industry experience required.

• Highly organized and self-motivated, with the ability to work independently as well as collaboratively within a team to conduct a high-level research project is crucial.

• Previous experience with mouse handling, dosing, tissue collection and processing is essential.

• Previous in-vivo work on mouse models of autoimmune disease is strongly preferred.

• Strong hands-on skills in basic biochemical and molecular techniques such as quantification of mRNA (qPCR), multi-panel flow cytometry (including both intracellular and extracellular markers) and protein expression; ELISA, Western blot, MSD, Luminex are strongly preferred. .

• Strong written and oral communication skills.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey.

When we put unexpected teams in the same room, we unleash ambitious thinking with the power to inspire life-changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.”

So, what’s next!

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en