Real World Evidence (RWE) Manager

This is what you will do:

• Lead the operational delivery of market-shaping, access-enabling and practice-changing real world evidence (RWE) studies aligned to strategic plans within rare diseases, collaborating with internal and external stakeholders to ensure success.
• Deliver evidence through implementation of innovative data solutions, including leading on data partnerships with the NHS developing novel analytical tools and platforms and supporting market access activities aligned to business and disease plans.

You will be responsible for:

RWE strategic leadership

• Supports and guides disease strategy in identifying and prioritising the most appropriate RWE solutions to meet strategic business needs, including opportunities to support policy, market-shaping and launch excellence, as well as to impact clinical practice and drive value based health care initiatives.
• Ability to collaborate and communicate effectively with a variety of stakeholders, bringing RWE medical leadership and technical expertise into business discussions

RWE Study delivery

• Delivers RWE studies using appropriate methodologies and data sources to generate required evidence for the portfolio including the creation of high quality study documents (ie study design concepts, protocols) and working with local and global colleagues to ensure smooth progression of studies through internal and external governance processes
• Analyses real world data (RWD) sources (including electronic health records, rare disease registries) to identify RWE opportunities within the rare disease portfolio, working in collaboration with cross functional stakeholders, including the AstraZeneca RWE teams.
• Project manages 3rd party agencies and vendors to deliver RWE projects as required
• Successfully deliver the RWE plan using a balance of technical expertise, therapeutic knowledge, project management and communication skills, leveraging and prioritising internal and external resources as required
• Responsible for ensuring GxP requirements and other regulation and compliance considerations related to evidence generation activities are met

You will need to have:

• Degree in epidemiology or life sciences (or appropriate equivalent)
• Strategic and operational planning specifically focussed on identifying evidence needs and prioritised solutions
• Strong ability to understand, interpret and communicate statistical analyses
• Experience of delivering research using UK electronic health record databases, disease registries and other RWE methodologies (ie medical chart review)
• Knowledge of the UK health data landscape and how this is evolving
• Track record of managing development, analysis and publication of RWE studies
• Project management experience
• Evidence of collaborative team working and personal accountability

We would prefer for you to have:

• Post graduate qualification in relevant subject (biostatistics, public health, epidemiology etc)
• Pharmaceutical industry experience
• Experience in rare diseases
• Technical skills: Protocol writing, statistics, analytical skills
• Knowledge of the UK rare disease data landscape, including disease registries
• Knowledge and experience of data interoperability, Natural Language Processing, Machine Learning/ AI in health data analyses.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.