Thesis work, 30 credits - Enhancing Drug Delivery with Self-Nanoemulsifying Drug Delivery Systems

Are you interested in pharmaceutical research and drug delivery technologies? Join us to advance innovative solutions in drug formulation! 

About AstraZeneca: 

AstraZeneca is a global, science-led, patient-centred biopharmaceutical company focusing on discovering, developing, and commercialising prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.  

About the Opportunity: 

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business. 

Thesis work description:  

This project focuses on advancing research into Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) and mesoporous materials for improving the delivery of poorly soluble drugs. You will explore cutting-edge lipid-based formulations and their potential applications in enhancing drug solubility and bioavailability. 

Key Objectives: 

• Optimize SNEDDS Formulation - Develop and characterize self-nanoemulsifying formulations that effectively enhance the solubility of poorly soluble drugs. 
• Evaluate Compatibility with Mesoporous Materials - Investigate the loading capacity and interactions of SNEDDS within mesoporous matrices to ensure stability and bioavailability. 
• Assess Drug Release Profiles - Conduct in vitro studies to analyze the release profiles of drugs from both SNEDDS in capsules and formulations within mesoporous tablets. 
• Enhance Tablet Formulation Techniques - Explore compression techniques for producing tablets from mesoporous materials loaded with SNEDDS to achieve optimal drug delivery. 
• Contribute to Drug Delivery Science - Provide valuable insights and advancements in the field of drug delivery that may lead to more effective therapeutic options for patients. 

Essential Requirements: 

• Ongoing master’s studies within Pharmacy or Process Engineering 

So, what’s next?  

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can´t wait to hear from you!  

We welcome your application as soon as possible, but ahead of the scheduled closing date 27th of April 2025. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.