Scientist

Scientist

The Early Discovery Oncology IHC team at AstraZeneca in Gaithersburg, MD is seeking a highly motivated scientist with a proven track record in histology and immunohistochemistry. The successful candidate will work independently and in collaboration with others to conduct scientific research as part of a team effort. The candidate will be responsible for the development of IHC/ISH methods, tissue sectioning, and other histological techniques, as needed. In this cross-functional role, the selected candidate will participate in project teams and work in a multidisciplinary environment to advance projects.

Accountabilities

• Assists the team in the development of IHC/ISH assays in support of early target discovery. Communicates results to team members.
• Assesses and reports data in a clear and concise manner, while understanding the implications to the overall context of drug discovery.
• Will perform microtomy sectioning for the early oncology team.
• Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations.
• Assists in the ordering and organization of necessary reagents and supplies for the histology lab.
• Will learn how to independently operate autostainers to help team generate data and support the maintenance upkeep of all automated systems.

Essential Skills/Experience

• Bachelor's Degree in biology, immunology or other relevant biological discipline, with 2-4 years of work experience OR a Master's Degree with 0 years of experience.
• Ideal candidate should have a background in research and some exposure to immunohistochemistry and histology techniques.
• The position is a hands-on, primarily laboratory-based position.
• An organizational skillset is essential to the role.
• Responsible for the application of immunohistochemistry principles and techniques to help validate new targets.
• Prepares precise technical summaries, protocols and all appropriate documentation of experiments in laboratory notebooks.
• Responsible for the correct operation and utilization of lab equipment, and overall state of the shared lab space.
• Will be responsible for establishing working relationships and credibility with department members and others within the company.
• This position requires excellent oral and written communication skills.
• Ability to prioritize and work in a fast-paced, matrixed environment is required.

Desirable Skills/Experience

• The successful applicant will have a desire to learn basic human tissue histology and identification of basic elements of tissue under the microscope.
• Candidate will be familiar with the use and application of Westerns and flow cytometry as they pertain to the validation of commercial antibodies.

At AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs. We are united in our vision to eliminate cancer as a cause of death, making bold moves that transform treatment and improve patient outcomes. Our collaborative environment draws on diverse knowledge from across the business and external partners, empowering us to take smart risks, challenge norms, and learn from failures. Join us at the forefront of applying science to studies, using innovative approaches to create new possibilities!

Ready to make a difference? Apply now!

The annual base pay for this position ranges from $87,200.00 - 130,800.00. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.