Medical Director, Early Clinical Development - Gastroenterology

In the Respiratory and Immunology Early Clinical Development team, we are investigating the drivers of key immunological diseases, with access to groundbreaking science, innovative drug discovery approaches, and key collaborations with academic centers around the world. We are exploring a range of drug modalities – small molecules, biologics, oligonucleotides, and cell therapies – across multiple diseases with high unmet medical need.

Early Clinical Development is where science meets clinical drug development with a focus on delivering innovative, early-phase clinical studies (Phase 1 and 2), while collaborating closely with our late-phase clinical development colleagues who guide our registrational clinical studies. We collaborate with bioscientists and translational medicine colleagues to define our early-phase clinical development strategies, design innovative Phase 1 and 2 clinical trials, develop and validate new clinical endpoints, and translate scientific ideas to proof-of-concept studies in targeted patient populations.

Accountabilities

As an Early Clinical Development Medical Director with a focus on Gastroenterology, you will contribute to early Phase I and 2 global clinical trials and related clinical research projects for compounds targeting immunology indications. You will serve as an expert on the design, conduct, monitoring, data interpretation, and reporting of these studies. Additionally, you will work on cross-functional teams within our ECD group and across the broader early R&I organization that are framing our strategies and development plans for compounds across indications, including asthma, COPD, and additional immunology indications.

You will take ownership for clinical development in cross-functional teams to support early-phase activities. These activities include the creation of overall clinical development plans and clinical study design as well as writing protocols, key study and health authority documentation, medical monitoring, and ensuring timely delivery of studies, all in collaboration with relevant internal and external partners and clinical research organizations.

Essential Skills/Experience

- Fully qualified physician (MD, MBBS or equivalent)

- A Gastroenterology background by specialty training and/or Clinical Drug Development

- 2+ years of experience in clinical development including experience in the design, monitoring, implementing and interpreting clinical trials, with understanding of biomarkers, biostatistics and safety reporting

- Excellent collaboration, communication, presentation skills

Desirable Skills/Experience

- US Board Certification preferred

- MD/PhD

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Remote or travel constructs are not available for this position.

The annual base pay for this position ranges from $241,614 to $362,420. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

At AstraZeneca, we are at the cutting edge of science, rethinking the future of medicine for the industry, ourselves, and patients. Work on groundbreaking medicine discovery and development from early to late stage and be at the forefront of answering some of the most complex unmet patient needs. Join the brightest minds and best talent where there's huge opportunity to drive change. Empowered to explore areas that have never been seen before, apply creativity and innovation to find pioneering new solutions.

Ready to make a difference? Apply now!