Oncology R&D Summer Internship

We are seeking three undergraduate Juniors, Master-level, or PhD-level students, working towards a degree in biology, biochemistry, cancer biology, molecular biology, cell biology, biopharmaceutical/pharmaceutical science, biomedical science, or other related field, for a 12-week Student Intern role in Gaithersburg, MD for a May 19th - August 8th contract period.

This posting is for the following three internship projects:

Investigating and validating biomarkers of resistance to ADC payloads

• Generation and culturing of cell lines resistant to ADC payloads.
• Validate biomarkers identified from multi-omic analyses by conducting Western blots and imaging studies.
• Work with BioInfomatics/Data Sciences to compare parental cells to resistant cells.
• Use cytotoxicity assays to confirm that payload resistant cells are also resistant to ADCs conjugated with those payloads.
• Collaborate with team members and participate in meetings.
• Present project findings at the end of the internship period.
• Analyze and communicate research results to team members.

In vitro assay development for evaluation of tumor targeted conjugates

• Design, conduct, troubleshoot and analyze in vitro experiments using an array of biochemical, molecular and cellular biology techniques to validate new targets and dissect the mechanism of action of novel cancer therapeutics.
• Collaborate with team members and participate in meetings.
• Present project findings at the end of the internship period.
• Analyze and communicate research results to team members.

Deciphering mechanisms of cell surface expression and internalization of B7 immune regulators

• Design and perform experiments to study protein expression, protein internalization in advanced cell culture systems.
• Develop combination treatment with antibody-drug conjugates and characterize combination activity.
• Collaborate with team members and participate in meetings.
• Analyze and communicate research results to team members.
• Present project findings at the end of the internship period.

Position Requirements:

• Undergraduate Juniors, Master-level, or PhD-level students, working towards a degree in biology, biochemistry, biological science, cancer biology, molecular biology, cell biology, biopharmaceutical/pharmaceutical science, biomedical science or related field. **Candidates must have an expected graduation date after August 2025.
• Wet-lab and pipetting skills, liquid handling experience, and aseptic techniques knowledge.
• Tissue culture, cell-based assays, and Western Blot analyses experience is required.
• Familiarity with bioinformatics tools, immunofluorescence microscopy, flow cytometry, transfection/transduction of cells, and qPCR.
• Proficiency in Microsoft Office Suite.
• Enthusiasm for collaboration, cross-functional projects, public speaking, and presentation design.
• Ability to report onsite to Gaithersburg, MD five days a week. This role will not provide relocation assistance.
• Minimum grade point average of 3.0.