Sr. Director, Oncology Diagnostic Assays

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.

As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026. Find out more information here: Kendall Square Press Release

The Role

Follow the science and pioneer new frontiers. Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us. With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Have the opportunity to build an exciting and meaningful career as part of the team committed to improving the lives of millions with cancer.

As a Senior Director, Oncology Diagnostic Assays you will…

• Define strategies and lead AstraZeneca’s response to enable trials using biomarkers to both get patients on the right treatment and to gauge treatment efficacy as soon as possible with an initial emphasis on circulating tumor DNA technologies.
• Provide expert advice, influencing the development of technology and data analytics internally and with partner organisations relevant to current and anticipating future Global Clinical Development
• Effectively integrate data on new compounds and information on targeted diseases into strategy to ensure innovative support for drug development projects
• Liaise with the internal and external medical and technology community to follow developments within areas of expertise
• Act as a subject matter expert including governance review of strategic and specific initiatives
• Lead regulatory communication and preparation of higher-level documents
• Manage or support complex and groundbreaking projects to improve processes within Translational Science or develop and introduce new technologies and approaches at the national, regional or global level
• Ensure that your own work and work of function is aligned with Good Laboratory Practice, Safety Health and Environment standards and all other relevant internal and external regulation and standards

Required Education, Experience & Skills

• PhD or equivalent, MD or equivalent strongly preferred
• Experience of the development and application of circulating tumor DNA assays for clinical use
• 5+ years of experience in aligned to the drug development or process in industry or academia or equivalent
• Extensive experience of crafting and implementing clinical trials using novel biomarker approaches for the earlier identification of patients
• Well-developed understanding of biomarker analysis
• Experience of communicating complex science to a clinical audience including external professional and regulatory bodies

• Proven experience managing and designing clinical trials

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Are you ready to make a difference? Apply today!

Are you interested in working at AZ, apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.