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Therapy Area Lead - Respiratory & Immunology (R&I) Genomics

Ort Cambridge, England, Vereinigtes Königreich Anzeigen-ID R-105183 Veröffentlichungsdatum 04/12/2021

Therapy Area Lead - Respiratory & Immunology (R&I) Genomics

Location: Cambridge UK /  Gothenburg, Sweden or Waltham, US

Competitive Salary & Excellent Company Benefits

Diverse Minds. Go further with bold new opportunities. Collaborate with diverse minds

A highly visible, senior opportunity leveraging population-scale human genetics to fundamentally advance the way that new medicines are discovered, and ensure the right medicines are developed for the right patients in the most efficient way. Collaborating in an inclusive environment, a place full of bold new opportunities. And in return… we’re looking for people who are open and respectful, ambitious and driven.

Who we are

We are the AstraZeneca Centre for Genomics Research (CGR), launched in April 2016 with the  bold ambition to analyse two million human genomes by 2026. Using high-quality exome and genome sequence data and state-of-the-art methods for genomic analysis, CGR is uncovering genetic causes of disease and integrating genomics across the entire drug discovery and development platform. This work is fundamental to driving the discovery of higher quality novel precision medicines and successful transition into the clinic.

Who you are

We are seeking a talented  scientist or physician scientist with a background or career interest in applying human genomics to drug discovery to support our growing portfolio of projects, in the Respiratory and Immunology area of the Centre. You will be a member of the Centre’s Leadership team, reporting directly to the Head of Centre. You thrive working in collaborations with experts both in the CGR and the R&I therapy area and you’re looking for that next career challenge in a Director level role.

What you’ll do

You will coordinate an expert team of genomic scientists to build an improved understanding of human disease and its treatment through state-of-the-art analytical methods. You will thrive on the application of your clinical / drug development expertise to collaborate closely with colleagues in all stages of drug discovery and development to ensure robust and well-validated projects are efficiently progressed. Your accountability will span across the scientific leadership and strategy of all respiratory & immunology genomics projects. Additionally, you will be the senior representative of the CGR at therapy area working groups, having a seat in the CGR leadership team and reporting to the Head of CGR.

You will have matrix management responsibilities delivering through collaboration with CGR and disease area specialists. Both new and ongoing genomics collaborations within respiratory and immunology disease area, as well as counselling senior partners on genomics aspects of projects and business plans will be part of your responsibility. You will be a pivotal member of the team contributing to scientific innovation, strategic alignment, prioritisation and sharing of genomic data to transform drug research and development. Depending on your previous experience and expertise, this role could be at either Associate Director or Director level.

Key Responsibilities

  • Partner with senior colleagues in the R&I therapy area to deliver the CGR genomics strategy
  • Coordinate the expert CGR team to deliver Genomics projects aligned to R&I strategy
  • Identify new external collaborators and manage existing Academic collaborations
  • Close collaboration with R&I Therapy area decision makers to achieve consensus on strategy alignment, prioritisation and effective integration of Genomics data into the drug discovery pipeline
  • Contribute to and present at key governance review boards and leadership team meetings
  • Partner with required CGR functions to ensure delivery of high quality projects, including analytics, portfolio management, business development, finance and communications
  • Lead CGR cross-functional interpretation of results and contributing to scientific publications in high-quality peer-reviewed journals and presentations at scientific conferences
  • As part of the CGR LT, define the overall CGR strategy and goals aligned to R&I disease strategy, including required budget and resources

Essential Criteria

If you share our desire to drive evolution in the understanding of human disease and transform the drug development process then please get in touch. We believe that you are a physician or a scientist (MD and/or PhD) with experience in research & development in the Biopharmaceutical industry and an interest in human genomics. Furthermore, you are a leader with experience in and passion for developing, motivating and empowering others and you do this by excellent communication.

  • A Background of matrix management promoting, motivating and empowering others to accomplish individual, team and organisational objectives
  • A track record of  successful contributions to drug discovery and development projects
  • Demonstrates conceptual, analytical and critical thinking
  • Effective leading of large cross-functional projects including internal and external stakeholders
  • Capability to formulate strategic genomics' direction for the Therapy area, communicating sophisticated scientific topics clearly to non-experts
  • Effective influencing, communication and partner leadership skills, including effective delivery through academic collaborations
  • High levels of integrity, patient-centric thinking and collaborative values

Desirable Criteria

  • External recognition as specialist in own specialism, confirmed by publications, external scientific presentations, awards, etc.
  • Demonstrated scientific leadership of how genomics can benefit the overall drug development process
  • Expertise in risk management and prioritisation relevant to genomics studies, such as regulatory, human bio samples and privacy aspects
  • Ability to influence strategically and persuade subtly, to acquire desired outcomes while maintaining effective, positive, organisational relationships

How we do it

Our values guide everything we do at AstraZeneca. They power our belief in What Science Can Do – a belief in its potential to redefine what’s possible.

Build a long-term career by unlocking opportunities for lifelong learning

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

So, what’s next?

Complete your application before the below closing date.

This role is open from 6 May 2021 and welcome with your application no later than 20 May 2021.

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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