HTA and Modelling Science Lead and Manager

Are you a passionate health economic modeller? Or love the application of health technology assessment (HTA) methodology to translate data into evidence to inform better decision-making? Would you like to apply your experience in a company that follows the science and turns ideas into life changing medicines? Then come and join us!

Working at AstraZeneca means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

To meet the needs of our growing pipeline and the external environment, AstraZeneca are investing in a new Centre of Excellence to support our HTA efforts around the world. Based in our global Barcelona hub, we have exciting opportunities for experienced, applied HTA methodologists to join one of our two HTA and Modelling Science (HMS) teams at either a Manager or Lead level. These two teams, that work closely together, are split by therapy area, covering either Oncology (our Oncology Business Unit (OBU)) or Cardiovascular, Renal & Metabolism and Respiratory & Immunology and Vaccines & Immune (our BioPharmaceutical Business Unit (BBU)).

In either team, and as part of a multi-disciplinary group, including HTA statisticians and market access specialists, you will be helping us to shape the payer environment, creating and delivering highly valued market access solutions that unlock the potential of our life-changing medicines for patients around the world.

What you’ll do

In this role, you will be responsible for the use and implementation of HTA methodology, such as economic modelling or indirect comparisons, for use in global HTA submissions and beyond, to support patients having access to our innovative medicines. With the growing use of HTA, including the upcoming Joint Clinical Assessment in Europe, you will play an important role in shaping what we do and how we do it, and not just in the delivery of analyses and tools, but also the interpretation and communication of their value to decision-makers.

By working cross-functionally within your disease area, and with your counterparts in the other global Business Units, you will help us transform the future of healthcare by unlocking the power of what science can do for people, society and the planet.

Development of our people is of most importance to us too. And, as part of our new Centre of Excellence, there will be the ability to learn and further develop skills, as well as opportunities to experience different therapy areas over time. Furthermore, your expertise is critical in our future vision and we hope you would share your skills with colleagues too.

Essential for the role

• Good understanding and ability of developing and building decision-analytic models, such as cost-effectiveness models, and / or conducting network meta-analyses (NMA) and indirect treatment comparisons (ITC).
• Undertaken or made meaningful contributions to HTA submissions
• Knowledge of global HTA systems and how their changing needs could influence AstraZeneca’s skill development
• Knowledge of drug development and reimbursement pull-through within the pharmaceutical or medical device industry.
• Understanding and ability to interpret clinical and statistical data
• Good communication, collaboration and interpersonal skills
• Good problem solving skills
• Degree in relevant field such as quantitative social sciences (e.g. economics, health economics, health services research), mathematical sciences (e.g. mathematics, statistics, operations research, engineering) or equivalent quantitative skill demonstration (e.g. through development in the workplace).

Our Manager and Lead roles depend on the level of experience. Examples of what would be desirable for the Lead role could include:

• Strong understanding and experience in both indirect comparisons and economic models
• A strategic knowledge of global HTA systems and how HTA methods can be applied across the business and maximise reimbursement opportunities and patient access to our medicines.
• Regional or global HTA submission experience (for example, submissions across multiple countries)
• Ability to communicate complex problems and solutions in a suitable way
• Worked within a pharmaceutical industry and cross-matrix environments