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Research Scientist, Mechanistic Biology & Profiling

Ort Waltham, Massachusetts, USA Anzeigen-ID R-078739 Veröffentlichungsdatum 04/06/2020

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration through scientific research. Here, employees are empowered to express diverse perspectives and are made to feel valued, energized and rewarded for their ideas and creativity.

Discovery Sciences is a multi-faceted department which drives early drug discovery across AstraZeneca’s global Research & Development portfolio. Mechanistic Biology & Profiling (part of Discovery Sciences), is a global, multidisciplinary department responsible for mechanism-of-action studies and compound profiling for efficacy and pre-clinical safety in support of the Oncology, Cardiovascular and Renal Disease, Respiratory, Inflammation & Autoimmunity, and Neuroscience portfolios.

Key Responsibilities:

Reporting directly to the US Associate Director of the Mechanistic Biology & Profiling Department you will be an integral member of a team generating pre-clinical pharmacology data to predict and understand compound (and novel drug modalities) efficacy to drive our DMTA cycle (Design, Make, Test, Analyze).

You will provide early, impactful insight to projects across the Oncology and Neuroscience disease areas, through a combination of in vitro enzymology, and pharmacology. You will be a skilled and passionate lab-based scientist, able to represent the department across a range of therapeutic projects and global initiatives, and externally, too.

Essential Requirements:

Masters and a minimum of 1 year of relevant experience or Bachelors with a minimum of 3 years of relevant experience

Experience must be gained in the pharmaceutical/biotechnology industry with proven experience in a quantitative biology-based discipline (enzymology, pharmacology,)

  • External reputation in pharmacology and/or enzymology, gained through professional recognition, external presentation,  publication in high-impact journals
  • Track record of delivering results across a diverse project portfolio

Desirable Qualifications:

  • Experience in pre-clinical drug discovery using robotic platforms


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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